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From: TSS ()
Subject: SCRAPIE PROGRAM FY REPORT 2007
Date: December 4, 2007 at 10:34 am PST

SCRAPIE PROGRAM FY REPORT 2007


Prepared by National Center for Animal Health Programs Ruminant Health
Programs Team November 15, 2007


snip...


Infected and Source Flocks


During FY 2007, there were a total of 76 new infected or source flocks
identified. Of those new flocks identified, 30 were infected flocks and 46
were source flocks (Figure 2). As of September 30, 2007, there were 38
scrapie infected and source flocks with open statuses (Figure 3). ...


snip...


In FY 2007, 331 scrapie cases have been confirmed and reported by the
National Veterinary Services Laboratories (NVSL), including 59* Regulatory
Scrapie Slaughter Surveillance (RSSS) cases (Figure 5 and Slide 16). In FY
2007, two field cases, one validation case, and two RSSS cases were
consistent with Nor-98 scrapie. The Nor98-like cases originated from flocks
in California, Minnesota, Colorado, Wyoming and Indiana respectively.
Nineteen cases of scrapie in goats have been reported since 1990 (Figure 6).
The last goat case was reported in September 2007.


snip...

see full report here ;

http://www.aphis.usda.gov/animal_health/animal_diseases/scrapie/downloads/yearly_report.pps

P03.141


Aspects of the Cerebellar Neuropathology in Nor98


Gavier-Widén, D1; Benestad, SL2; Ottander, L1; Westergren, E1
1National Veterinary Insitute, Sweden; 2National Veterinary Institute,
Norway


Nor98 is a prion disease of old sheep and goats. This atypical form of scrapie was first
described in Norway in 1998. Several features of Nor98 were shown to be different
from classical scrapie including the distribution of disease associated prion protein
(PrPd) accumulation in the brain. The cerebellum is generally the most affected brain
area in Nor98. The study here presented aimed at adding information on the
neuropathology in the cerebellum of Nor98 naturally affected sheep of various
genotypes in Sweden and Norway. A panel of histochemical and immunohistochemical
(IHC) stainings such as IHC for PrPd, synaptophysin, glial fibrillary acidic protein,
amyloid, and cell markers for phagocytic cells were conducted. The type of histological
lesions and tissue reactions were evaluated. The types of PrPd deposition were
characterized. The cerebellar cortex was regularly affected, even though there was a
variation in the severity of the lesions from case to case. Neuropil vacuolation was
more marked in the molecular layer, but affected also the granular cell layer. There was
a loss of granule cells. Punctate deposition of PrPd was characteristic. It was
morphologically and in distribution identical with that of synaptophysin, suggesting
that PrPd accumulates in the synaptic structures. PrPd was also observed in the
granule cell layer and in the white matter. The pathology features of Nor98 in the
cerebellum of the affected sheep showed similarities with those of sporadic
Creutzfeldt-Jakob disease in humans.


http://www.prion2007.com/pdf/Prion%20Book%20of%20Abstracts.pdf

NOR-98 ATYPICAL SCRAPIE USA UPDATE AS AT OCT 2007


typical scrapie transmits to primates by there NON-FORCED ORAL CONSUMPTION ;


76/10.12/4.6


http://www.bseinquiry.gov.uk/files/yb/1976/10/12004001.pdf


http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=ShowDetailView&TermToSearch=6997404&ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVAbstractPlus

full text ;


http://nor-98.blogspot.com/


http://scrapie-usa.blogspot.com/


CREUTZFELDT JAKOB DISEASE MAD COW BASE UPDATE USA


http://cjdmadcowbaseoct2007.blogspot.com/


Transmissible Mink Encephalopathy TME


http://transmissible-mink-encephalopathy.blogspot.com/


CHRONIC WASTING DISEASE


http://chronic-wasting-disease.blogspot.com/


Monitoring the occurrence of emerging forms of Creutzfeldt-Jakob disease
inthe United States


http://cjdusa.blogspot.com/

i am reminded of a few things deep throat (high ranking official at
usda)told me years ago;

==========================================

The most frightening thing I have read all day is the report of Gambetti's
finding of a new strain of sporadic cjd in young people.........Dear God,

https://www.blogger.com/comment.g?blogID=7842737484277562285&postID=5759550357128128100


CJD QUESTIONNAIRE

http://cjdquestionnaire.blogspot.com/

TSS




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