SEARCH VEGSOURCE:

 

 

Follow Ups | Post Followup | Back to Discussion Board | VegSource
See spam or
inappropriate posts?
Please let us know.
  




From: TSS ()
Subject: EVALUATION OF A RAPID ANTE MORTEM BSE TEST
Date: December 22, 2006 at 8:32 am PST

EVALUATION OF A RAPID ANTE MORTEM BSE TEST

Scientific Report of the

Scientific Expert Working Group of the European Food Safety Authority on

Transmissible Spongiform Encephalopathy (TSE)1

Adopted on 27 November 2006

Question N° EFSA-Q-2003-084

Summary

The European Food Safety Authority (EFSA) and its Scientific Expert Working Group on

Transmissible Spongiform Encephalopathy (TSE) Testing were asked by the European

Commission (EC) to take over the mandate of the former Scientific Steering Committee (SSC)

for the scientific evaluation of rapid TSE/BSE (Bovine Spongiform Encephalopathy) tests. At

present 12 rapid BSE test kits are approved by the EC for the post mortem testing of

slaughtered cattle in accordance with the TSE Regulation (EC) No 999/2001. Following an EC

call for expression of interest in the Official Journal of the European Union (No C15) on 22

January 2003, several parties indicated their interest in participating in the third European

evaluation exercise for newly developed rapid post mortem and live animal TSE/BSE tests.

Expressions of interest were invited from those who had tests in advanced stages of

development or available for use for the diagnosis of BSE in live cattle. Applications were

received from six companies presenting six different tests. In order to ensure that useful tests

would be widely available, applicants were also requested to give assurances that they were

prepared to make their tests available on a non discriminatory basis following the evaluation. A

panel of external scientists assessed all applications based on the pre-defined criteria, covering

e.g. the scientific basis of the test, available experimental evidence, practicality of the sampling

and testing procedures and stage of development of the test. Following this assessment 1 test

was selected for the evaluation exercise. This joint application was presented by two

companies: Scil Diagnostics GmbH, Martinsried, Germany and DiaSpec GmbH, Freiburg,

Germany for the “AquaSpec BSE” rapid ante mortem test. Evaluation was based on the EFSA

Scientific Report on the Design of a Field Trial Protocol for the evaluation of BSE Tests for

Live Cattle adopted on 1 July 2004. On 10 October 2006, EFSA has received the report of the

European Commission’s Institute of Reference Materials and Measurements (IRMM) on the

evaluation of DiaSpec’s rapid ante mortem BSE test (IRMM, 2006).

Based on the overall assessment covering the application dossier and a phase I laboratory

evaluation, the experts of EFSA´s Working Group on TSE Testing express their opinion on the

1 For citation purposes: Scientific Report of the European Food Safety Authority on Transmissible

Spongiform Encephalopathy (TSE) on a request from the European Commission on the evaluation of a

rapid ante mortem BSE test, The EFSA Journal (2006) 95, 1-14

http://www.efsa.europa.eu/etc/medialib/efsa/science/tse_assessments/bse_tse/report_ej95_animal.Par.0002.File.dat/biohaz_sr_ej95_live_animal_bse_test_summary_en.pdf

SEE FULL TEXT ;

http://www.efsa.europa.eu/etc/medialib/efsa/science/tse_assessments/bse_tse/report_ej95_animal.Par.0001.File.dat/biohaz_sr_ej95_live_animal_bse_test_en.pdf

SEE OTHER EVALUATIONS ON BSE RAPID TEST HERE;

http://www.efsa.europa.eu/en/science/tse_assessments/bse_tse.html

TSS




Follow Ups:



Post a Followup

Name:
E-mail: (optional)
Subject:

Comments:

Optional Link URL:
Link Title:
Optional Image URL: