SEARCH VEGSOURCE:

 

 

Follow Ups | Post Followup | Back to Discussion Board | VegSource
See spam or
inappropriate posts?
Please let us know.
  




From: TSS ()
Subject: USA MINK FARMS AND TSE TESTING ???
Date: July 15, 2006 at 5:52 am PST

Pelt Production Up 3 Percent

Mink pelt production in the United States in 2005 totaled
2.63 million pelts, up 3 percent from 2004. Wisconsin, the largest
mink producing State, produced 778,000 pelts. Utah the second
largest producing State, produced 600,000 pelts.

The number of pelts by color class as a percent of the total U.S.
production in 2005 is as follows: Black at 47.6 percent, Mahogany
at 20.9 percent, Blue Iris at 11.3 percent, Demi/Wild at
6.3 percent, Sapphire at 4.0 percent, and White at 3.8 percent.
The remaining color classes accounted for 6.1 percent.

Value of Pelt Production Up 33 Percent

Mink pelts produced during the 2005 crop year were valued at
$160 million, up 33 percent from $120 million a year ago. The
average price per pelt for the 2005 crop year was $60.90, up from
$47.10 in 2004. .....snip.......end

http://usda.mannlib.cornell.edu/reports/nassr/other/zmi-bb/mink0706.pdf

TME

http://www.aphis.usda.gov/lpa/pubs/fsheet_faq_notice/fs_ahtme.html


Title: Experimental Inoculation of Tme, Scrapie, and Cwd to Raccoons: An Update

Authors

Hamir, Amirali
Miller, Janice - ARS RETIRED
Cutlip, Randall - ARS RETIRED
Stack, Mick - VLA-WEYBRIDGE, UK
Chaplin, Melanie - VLA-WEYBRIDGE, UK
Bartz, Jason - CREIGHTON UNIVERSITY
Jenny, Allen - USDA, APHIS, NVSL
Williams, Elizabeth - UNIVERSITY OF WYOMING


Submitted to: Meeting Abstract
Publication Type: Abstract
Publication Acceptance Date: September 29, 2004
Publication Date: October 14, 2004
Citation: Hamir, A., Miller, J., Cutlip, R., Stack, M., Chaplin, M., Bartz, J., Jenny, A., Williams, E. 2004. Experimental Inoculation of Tme, Scrapie, and Cwd to Raccoons: An Update [abstract]. Animal Prion Diseases and the Americas. P. 79.

Technical Abstract: Raccoons (Procyon lotor) are omnivorous and their diet may include carrion. It is, therefore, possible that in the wild they may get exposed to carcasses of animals with transmissible spongiform encephalopathies (TSEs). To determine the susceptibility of raccoons to transmissible mink encephalopathy (TME), scrapie, and chronic wasting disease (CWD), each of these agents was inoculated intracerebrally into a group of 4 kits. Three uninoculated kits served as controls. All raccoons in the TME-inoculated group developed neurologic signs and were euthanized within 6 months post inoculation (PI). In the scrapie-inoculated group, 3 animals became sick and were euthanized between 18 - 22 PI. Although the fourth raccoon in this group did not show any clinical signs, it was euthanized at 24 months PI. At necropsy all clinically affected raccoons had extensive microscopic lesions of spongiform encephalopathy and protease-resistant prion protein (PrPres) was detected in the CNS by immunohistochemistry and Western blot. In the CWD-inoculated group, 1 raccoon was euthanized at 39 months PI because of severe cystitis. Its brain was negative for PrPres. At present, 5 years PI, the 3 remaining CWD-inoculated raccoons are alive and apparently healthy. They will be kept under observation for further period of 1 year (i.e 6 years PI) when the experiment will be terminated. These preliminary findings demonstrate that TME and scrapie can be transmitted to raccoons within 6 months and 2 years, respectively, whereas CWD cannot. Based on these incubation periods, it may be possible to differentiate these 3 TSEs. Such a laboratory model would be relatively simple, fast and inexpensive for strain-typing of unknown TSEs in the United States. Now that the relative susceptibiity to IC transmission of each TSE has been established, oral transmission studies of TSEs to raccoons are planned.




Last Modified: 07/14/2006


http://www.ars.usda.gov/research/publications/publications.htm?seq_no_115=167761


Research Project: Transmission, Differentiation, and Pathobiology of Transmissible Spongiform Encephalopathies
Location: Virus and Prion Diseases of Livestock

Title: Experimental Transmission of Transmissible Mink Encephalopathy (Tme) to Cattle by Intracerebral Inoculation


Authors

Hamir, Amirali
Kunkle, Robert
Miller, Janice - ARS RETIRED
Greenlee, Justin
Richt, Juergen


Submitted to: International Veterinary Vaccines and Diagnostics Conference
Publication Type: Abstract
Publication Acceptance Date: March 15, 2006
Publication Date: June 25, 2006
Citation: Hamir, A.N., Kunkle, R.A., Miller, J.M., Greenlee, J.J., Richt, J.A. 2006. Experimental Transmission of Transmissible Mink Encephalopathy (Tme) to Cattle by Intracerebral Inoculation [abstract]. 4th International Veterinary Vaccines and Diagnostics Conference. P. 89. Paper No. Po53.

Technical Abstract: To compare clinicopathological findings of transmissible mink encephalopathy (TME) with other transmissible spongiform encephalopathies (TSE, prion diseases) that have been shown to be experimentally transmissible to cattle (sheep scrapie, and chronic wasting disease, CWD), 2 groups of calves (n = 4 each) were intracerebrally inoculated with TME agents from 2 different sources (mink with TME and a bovine with TME). Two uninoculated calves served as controls. Within 15.3 months post inoculation (PI), all animals from both inoculated groups developed clinical signs of central nervous system (CNS) abnormality; their CNS tissues had microscopic spongiform encephalopathy (SE); and PrP**res was detected in their CNS tissues by immunohistochemistry (IHC) and Western blot (WB) techniques. These findings demonstrate that intracerebrally inoculated cattle not only amplify TME PrP**res but also develop clinical CNS signs and extensive lesions of SE. The latter has not been shown with other TSE agents (scrapie and CWD) similarly inoculated into cattle. The findings also suggest that the diagnostic techniques currently used for confirmation of bovine spongiform encephalopathy (BSE) would detect TME in cattle should it occur naturally. However, it would be a diagnostic challenge to differentiate TME in cattle from BSE. Our recent preliminary results indicate that WB may be able to differentiate between bovine TME and BSE.


http://www.ars.usda.gov/research/publications/publications.htm?seq_no_115=191825

Research Project: Transmission, Differentiation, and Pathobiology of Transmissible Spongiform Encephalopathies
Location: Virus and Prion Diseases of Livestock

Title: First and Second Cattle Passage of Transmissible Mink Encephalopathy (Tme) by Intracerebral Inoculation


Authors

Hamir, Amirali
Kunkle, Robert
Miller, Janice - ARS RETIRED
Bartz, J - CREIGHTON UNIVERSITY
Richt, Juergen


Submitted to: Veterinary Pathology
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: August 12, 2005
Publication Date: March 1, 2006
Citation: Hamir, A.N., Kunkle, R.A., Miller, J.M., Bartz, J.C., Richt, J.A. 2006. First and Second Cattle Passage of Transmissible Mink Encephalopathy (Tme) by Intracerebral Inoculation. Veterinary Pathology. 43(2):118-126.

Interpretive Summary: Transmissible mink encephalopathy (TME) is a fatal neurologic disease. It is similar to bovine spongiform encephalopathy (BSE) or mad cow disease. To compare TME infection with other similar diseases in cattle, 2 groups of calves were inoculated in the brain with TME agents from 2 different sources. Two uninoculated calves served as controls. Within 15.3 months post inoculation, animals from both inoculated groups developed clinical signs of central nervous system (CNS) abnormality. Laboratory tests revealed lesions and presence of the TME agent in their tissues. Both findings could not be differentiated from those seen in BSE. Our findings also demonstrated that the laboratory tests that are currently used for BSE surveillance would detect TME in cattle should it occur naturally. However, it would be a diagnostic challenge to differentiate TME in cattle from BSE by clinical signs or laboratory tests that are currently available. Results of this study will have an impact on directing future research on TSEs to search for specific laboratory tests to differentiate BSE from TME in cattle.
Technical Abstract: To compare clinicopathological findings of transmissible mink encephalopathy (TME) with other transmissible spongiform encephalopathies (TSE, prion diseases) that have been shown to be experimentally transmissible to cattle (sheep scrapie, and chronic wasting disease, CWD), 2 groups of calves (n = 4 each) were intracerebrally inoculated with TME agents from 2 different sources (mink with TME and a bovine with TME). Two uninoculated calves served as controls. Within 15.3 months post inoculation (PI), animals from both inoculated groups developed clinical signs of central nervous system (CNS) abnormality; their CNS tissues had microscopic spongiform encephalopathy (SE); and PrPres was detected in their CNS tissues by immunohistochemistry (IHC) and Western blot (WB) techniques. These findings demonstrate that intracerebrally inoculated cattle not only amplify TME PrPres but also develop clinical CNS signs and extensive lesions of SE. The latter has not been shown with other TSE agents (scrapie and CWD) similarly inoculated into cattle. The findings also demonstrate that the diagnostic techniques currently used for bovine spongiform encephalopathy (BSE) surveillance would detect TME in cattle should it occur naturally. However, it would be a diagnostic challenge to differentiate TME in cattle from BSE by clinical signs, neuropathology, or the presence of PrPres by IHC and WB.

http://www.ars.usda.gov/research/publications/publications.htm?SEQ_NO_115=173819


Greetings,

I would be curious if anyone on the list knows about TSE testing in the USA on mink farms?

WHAT sort of TME surveillance program is in place?

DO they still test for TSE in Mink and what are these figures?


thanks, terry



Follow Ups:



Post a Followup

Name:
E-mail: (optional)
Subject:

Comments:

Optional Link URL:
Link Title:
Optional Image URL: